Welcome to the Pharmaceutical Bioinformatics research group at Uppsala University

Principal Investigator: Ola Spjuth

Research focus: Intelligent systems for drug discovery and chemical safety

The Pharmaceutical Bioinformatics research group focuses on mathematical and statistical modeling, informatics and quantitative analysis of pharmacological systems. We develop methods, algorithms and software to study and model pharmaceutical interactions, and a key focus in the group is how artificial intelligence (AI) and machine learning can aid the drug discovery process; e.g. in drug screening and when studying drug toxicity, metabolism and resistance. We combine in silico and in vitro experiments at the cellular level, and have a big focus on data analytics, informatics, and using modern e-infrastructure (such as high-performance and cloud computing). We are involved in several national and international consortia and have a tight connection to the pharmaceutical industry, Uppsala University Hospital, and Science for Life Laboratory. See the Projects page for more information on our ongoing research projects.

Latests Blog Posts

Ola Spjuth presenting at COPA 2019

10 Sep, 2019. Ola Spjuth presented two accepted papers at the 8th Symposium on Conformal and Probabilistic Prediction with Applications in Varna, Bulgaria on 9-11 sept 2019. The two papers below are now published in Proceedings of Machine Learning Resea ...

Two papers accepted for COPA2019 and published in PMLR

20 Aug, 2019. We are very proud to announce that we this year had 2 papers accepted to the 8th Symposium on Conformal and Probabilistic Prediction with Applications! Ola Spjuth will present the papers in Golden Sands, Bulgaria on 9-11 sept 2019. Paper ...

2 Open positions: PhD student and Lecturer; focus on AI/machine learning on large-scale data

4 Jul, 2019. Our research group has 2 open positions: One PhD position and one Lecturer position. Deadline for both applications is 2019-08-12. PhD Position Our group is participating in the HASTE project (Hierarchical Analysis of Temporal and Spatial ...

Ola Spjuth presented at SLAS Europe 2019

28 Jun, 2019. Ola Spjuth presented on the SLAS Europe 2019 conference, with the title of the presentation: “Building an informatics solution to sustain AI-guided cell profiling with high-content microscopy imaging“ Abstract High-content micr ...

SciPipe workflow tool published in GigaScience and CiSe

25 May, 2019. A few weeks ago the workflow tool we have developed and used in the group, SciPipe, was published in Gigascience. This article quite comprehensively summarizes our lessons learned in scientific workflow usage and design over the last coup ...

Ola Spjuth presented at Data Innovation Summit 2019

15 Mar, 2019. Ola Spjuth presented on the Data Innovation Summit 2019 conference, with the title of the presentation: “Automating the process of continuously prioritising data, updating and deploying AI models in a robotised lab for drug discovery ...

Successful FORMAS grant proposal: Exploring toxicity mechanisms for environmental contaminants using an AI-controlled automated laboratory

15 Nov, 2018. Group leader Ola Spjuth received a 3 MSEK grant from the FORMAS Future Research Leaders call in 2018, for a project with the title: Exploring toxicity mechanisms for environmental contaminants using an AI-controlled automated laboratory As ...

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