Welcome to the Pharmaceutical Bioinformatics research group at Uppsala University

Principal Investigator: Ola Spjuth

Research focus: Intelligent systems for drug discovery and chemical safety

The Pharmaceutical Bioinformatics research group focuses on mathematical and statistical modeling, informatics and quantitative analysis of pharmacological systems. We develop methods, algorithms and software to study and model pharmaceutical interactions, and a key focus in the group is how artificial intelligence (AI) and machine learning can aid the drug discovery process; e.g. in drug screening and when studying drug toxicity, metabolism and resistance. We combine in silico and in vitro experiments at the cellular level, and have a big focus on data analytics, informatics, and using modern e-infrastructure (such as high-performance and cloud computing). We are involved in several national and international consortia and have a tight connection to the pharmaceutical industry, Uppsala University Hospital, and Science for Life Laboratory. See the Projects page for more information on our ongoing research projects.

Latests Blog Posts

Successful FORMAS grant proposal: Exploring toxicity mechanisms for environmental contaminants using an AI-controlled automated laboratory

15 Nov, 2018. Group leader Ola Spjuth received a 3 MSEK grant from the FORMAS Future Research Leaders call in 2018, for a project with the title: Exploring toxicity mechanisms for environmental contaminants using an AI-controlled automated laboratory As ...

Samuel Lampa presented at Go Stockholm Conference

6 Oct, 2018. Samuel Lampa presented on the Go Stockholm 2018 conference, on the topic of “Using Flow-based programming to write tools and workflows for Scientific Computing in Go” (Slides available in the link). The talk described first som ...

Samuel Lampa successfully defended his PhD thesis: Reproducible Data Analysis in Drug Discovery with Scientific Workflows and the Semantic Web

28 Sep, 2018. Today, Samuel Lampa from the group successfully defended his thesis, titled: “Reproducible Data Analysis in Drug Discovery with Scientific Workflows and the Semantic Web“ CONGRATULATIONS SAMUEL! Supervisor: Assoc Prof. Ola Spj ...

CANCELLED: Dr. Konrad Hinsen presenting on "Building trust in Computational Science: From Reproducible to Verifiable Computer-aided Research"

29 Aug, 2018. Updated Sep 25: This event is cancelled due to scheduling obstacles! Time and Location Date: September 27, 2018, 15.00-16.00 (Attn: Time updated!) Location: Triple room (click for map), SciLifeLab, Biomedical Center (BMC), Husargatan 3, U ...

Upcoming Dissertation: Reproducible Data Analysis in Drug Discovery with Scientific Workflows and the Semantic Web

29 Aug, 2018. On September 28, Samuel Lampa from the group will defend his thesis, titled: “Reproducible Data Analysis in Drug Discovery with Scientific Workflows and the Semantic Web“ Supervisor: Assoc Prof. Ola Spjuth, Uppsala University ...

Summer-BBQ of 2018

14 Jun, 2018. This year again there was a summer-BBQ at Ola’s place. On June 14th the weather was very nice, and no one left hungry! This will definitely be a recurring event! ...

Niharika Gauraha presenting on COPA2018

12 Jun, 2018. Niharika Gauraha in the pharmb.io group presented her work at the conference Conformal Prediction and Probabilistic Predictions with Applicationsi (COPA) 2018 Conference website: http://www.clrc.rhul.ac.uk/copa2018/ Conformal Prediction in ...

More blog posts ...