Welcome to the Pharmaceutical Bioinformatics research group at Uppsala University

Principal Investigator: Ola Spjuth

Research focus: Intelligent systems with AI and machine learning in drug discovery and chemical safety

The Pharmaceutical Bioinformatics research group focuses on mathematical and statistical modeling, informatics and quantitative analysis of pharmacological systems. We develop methods, algorithms and software to study and model pharmaceutical interactions, and a key focus in the group is how artificial intelligence (AI) and machine learning can aid the drug discovery process; e.g. in drug screening and when studying drug toxicity, metabolism and resistance. We combine in silico and in vitro experiments at the cellular level, and have access to a robotized high-content imaging lab connected to a modern IT-infrastructure to manage and analyze large-scale data. We are involved in several national and international consortia and have a tight connection to the pharmaceutical industry, Uppsala University Hospital, and Science for Life Laboratory. See the Projects page for more information on our ongoing research projects.

Latests Blog Posts

Ola Spjuth presenting at Swedish e-Science Academy 2019

16 Oct, 2019. Ola Spjuth gave an invited talk at the conference Swedish e-Science Adademy 2019 in Lund, Sweden on 16 October 2019. The title of the talk was: Towards Automated AI-guided Drug Discovery Labs. Abstract High-content microscopy in automated ...

Marco Capuccini successfully defended his PhD thesis: Enabling Scalable Data Analysis on Cloud Resources with Applications in Life Science

10 Oct, 2019. Today, Marco Capuccini from the group successfully defended his thesis, titled: “Enabling Scalable Data Analysis on Cloud Resources with Applications in Life Science“ CONGRATULATIONS MARCO! Supervisor: Assoc Prof. Ola Spjuth, ...

Open position: PhD Project in Cell Biology with a focus on Intelligent Automation

7 Oct, 2019. We are looking for an ambitious, highly motivated PhD student with a good background in cell biology as well as interest in molecular biology, high-throughput screening, automation and bioinformatics. The successful candidate will join an i ...

Ola Spjuth presenting at COPA 2019

10 Sep, 2019. Ola Spjuth presented two accepted papers at the 8th Symposium on Conformal and Probabilistic Prediction with Applications in Varna, Bulgaria on 9-11 sept 2019. The two papers below are now published in Proceedings of Machine Learning Resea ...

Group Retreat at Krusenberg Mansion

28 Aug, 2019. On August 27-28, our research group was on a retreat to Krusenberg Mansion, where we had good presentations and discussed planning and strategies on research and education activities in the group. In the evening the social program involved ...

Two papers accepted for COPA2019 and published in PMLR

20 Aug, 2019. We are very proud to announce that we this year had 2 papers accepted to the 8th Symposium on Conformal and Probabilistic Prediction with Applications! Ola Spjuth will present the papers in Golden Sands, Bulgaria on 9-11 sept 2019. Paper ...

2 Open positions: PhD student and Lecturer; focus on AI/machine learning on large-scale data

4 Jul, 2019. Our research group has 2 open positions: One PhD position and one Lecturer position. Deadline for both applications is 2019-08-12. PhD Position Our group is participating in the HASTE project (Hierarchical Analysis of Temporal and Spatial ...

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