Welcome to the Pharmaceutical Bioinformatics research group at Uppsala University

Research focus: Data-intensive and translational bioinformatics

High-throughput technologies have transformed biomedicine into a data-intensive discipline. This has shifted the focus from traditional data generation and hypothesis testing to more data-driven research, and bioinformatics data analysis has become the bottleneck in many projects. However, the field is characterized by growing data sets and poorly scalable software, threatening to severely constrain many biomedical projects. Our group aims at developing new methods and applications to meet the demands of high-throughput biology and drug discovery, using high-throughput and cloud-based e-infrastructures and Big Data analytics.

Our paper: Large-scale virtual screening on public cloud resources with Apache Spark, got published in the Journal of Cheminformatics

7 Mar, 2017

Abstract Background Structure-based virtual screening is an in-silico method to screen a target receptor against a virtual molecular library. Applying docking-based screening to large molecular libraries can be computationally expensive, h ...
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Video from Marco Capuccinis talk at Spark Summit now online

14 Feb, 2017

As we have posted before, our colleague Marco Capuccini has been presenting at Spark Summit East 2017, with the title “EasyMapReduce: Leverage the power Of Spark And Docker To scale scientific tools In MapReduce fashion“ (click ...
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Our project: 'Hierarchical Analysis of Temporal and Spatial Image Data' will receive funding by SSF

9 Feb, 2017

Ola Spjuth is co-PI in the project ‘Hierarchical Analysis of Temporal and Spatial Image Data’ that received 29 MSEK from SSF for the period 2017-2021. Press release from Uppsala University Press release from SSF Abstract from th ...
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Presentation 'Analyzing Big Data in Medicine with Virtual Research Environments and Microservices' by Ola Spjuth on Uppsala University official YouTube Channel

26 Jan, 2017

This presentation was given by Ola Spjuth in the ‘Current Challenges in Biomedical Information Technology - Big Data in Medicine’ symposium series at the IT-department at Uppsala University. The slides are available from “ ...
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The 6th Symposium on Conformal and Probabilistic Prediction with Applications (COPA 2017)

24 Jan, 2017

14-16 June, 2017, Karolinska Institutet, Stockholm, Sweden. Ola Spjuth is local organizer of the event with the conference website: clrc.rhul.ac.uk/copa2017 Symposium Theme: Quantifying the uncertainty of the predictions produced by classif ...
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Marco Capuccini to present at Spark Summit East 2017

20 Dec, 2016

Marco Capuccini will present at Spark Summit East 2017: “EasyMapReduce: Leverage the power Of Spark And Docker To scale scientific tools In MapReduce fashion” Abstract: High-throughput methods in various scientific fields produc ...
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Ola Spjuth to present at CloudBeer 2017

19 Dec, 2016

Ola Spjuth will present at CloudBeer 2017 on March 23rd: “The case for cloud computing in the life sciences” Abstract: The life sciences is transforming into a data-intensive discipline with high demands on e-infrastructure. Clo ...
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